News • Are you a Nintendo Switch docker or hander? $299 Walmart $289 Amazon 0 See It $309 Post a comment Review • Nintendo Switch review: Pure fun on a big-screen TV or on the go Mentioned Above Nintendo Switch (Gray) Best Buy Nintendo CNET may get a commission from retail offers. Nintendo Switch How To • How to transfer your Nintendo Switch account to a new Switch V2 See it See It Gaming Share your voice Preview • Nintendo Switch: All the latest details $299 Nintendo of America President and COO Reggie Fils-Aime is retiring. Neilson Barnard/Getty Images Nintendo of America President and Chief Operating Officer Reggie Fils-Aime is retiring in April, the company said Thursday. Doug Bowser, currently the senior vice president of sales and marketing for Nintendo of America, will fill the role of president after Fils-Aime’s last day on April 15.”Nintendo owns a part of my heart forever,” Fils-Aime said in a statement. “It’s a part that is filled with gratitude — for the incredibly talented people I’ve worked with, for the opportunity to represent such a wonderful brand, and most of all, to feel like a member of the world’s most positive and enduring gamer community.”Fils-Aime began working at Nintendo of America in 2003 as executive vice president of sales and marketing. In 2006, he became president and COO. Under his leadership, Nintendo expanded its audience with products such as Brain Age, Wii Sports and Wii Fit, according to the release. Bowser, the next president, began working at Nintendo of America in 2015 as vice president of sales. He was promoted to senior vice president of sales and marketing the following year, and headed sales and marketing for Nintendo Switch. Before working at Nintendo of America, Bowser was an executive at Electronic Arts and held sales leadership positions at Procter & Gamble. Tags See It
Samidha SinghPR HandoutSamidha Singh is a renowned fashion and lifestyle blogger and stylist. She has collaborated with top brands in the world and has been a part of several big fashion shows. Samidha’s journey in the world of fashion is something that will leave everyone inspired.Singh studied Bachelors in Banking and Insurance from HR College in Mumbai and did Masters in Economis from Mumbai university. She has worked in a NBFC “Tata Capital” for two years as a credit underwriter. Samidha soon realised her passion fot fashion and wanted to do something in it.She resigned from her job and followed her passion for fashion. When she resigned, Samidha Singh told her parents that she can’t work in corporate world and do a desk job for 10-12 hours. She saved enough for her to decide how to go about fulfilling her dream of working in the fashion industry. She joined fashion designing in SNDT college and realised designing wasn’t her thing, but it was styling.She shared, “I used to get a lot of compliments about my style and there I came across ‘Fashion Blogging’. I researched about it and gave it a shot. I eventually started getting DMs from brands for barter collaborations. I still remember my first collaboration was with ‘Maddish the Style bar’, it was an instagram page where they sold stuff like bags and clothes. We did the collab but they never gave me my barter stuff. I was disgusted but I knew that if I have faith I can move ahead. And slowly I started getting barter collabs.”Life since then has been going well in fashion world for Samidha. She has been a part of London Fashion Week, Lakme Fashion Week, Goa Fashion Week, Bangalore Fashion Week and many others.
By The Associated PressDETROIT (AP) — A parking dispute at a social justice gathering in Detroit ended with a White business owner spitting on a Black security guard, who captured the altercation on video and posted it on Facebook.Ibrahim Mission was providing security at the event Tuesday when Detroit Mercantile Co. owner Robert Stanzler grew disgruntled over some participants parking on his property, the Detroit Free Press reported.In this July 18, 2018 photo, Ibrahim Mission sits outside The Eastern, an Eastern Market event space where Detroit Mercantile Co. Owner Robert Stanzler spat in his face during a dispute Tuesday, July 17, in Detroit. (Rochelle Riley/Detroit Free Press via AP)Stanzler asked Mission to stop people from parking near his business, which sells antiques and Michigan wares. Mission told Stanzler to speak to the building owner, and Stanzler responded by making an offensive hand gesture and spitting on Mission’s face.Maxyne Franklin said members of her group were moving their cars during the incident. Franklin said it was “outrageously disgusting behavior and completely unnecessary.”Police arrested Stanzler for simple assault. He was released Wednesday and apologized, calling his actions “unconscionable, offensive and disrespectful.”“I take full responsibility for my actions, and want to convey regret for my gross and despicable behavior during the course of my argument with Mr. Mission,” Stanzler said.He also apologized to those who witnessed the incident, his staff, other business owners in the area and Detroit residents.Mission, who grew up in Detroit, said he has worked security at many different types of events with people from all backgrounds.“I’ve encountered somebody saying a racial slur, somebody not being too happy with security, but never ran into where an individual, especially a White individual, felt comfortable enough to spit on me,” he said.Mission said Stanzler’s actions were humiliating and disrespectful.He said, “People like this should not be allowed to be in this community of Detroit and be able to feel they could take such liberties with helpers.”
© 2019 Science X Network Explore further An international team of researchers has succeeded in making 13,200 edits to a single cell—and the cell survived. In their paper uploaded to the bioRxiv preprint server, the team describes the edits they made, how they did it and why. Credit: CC0 Public Domain Distorted, stretched DNA may increase risk of off-target changes with CRISPR-Cas9 Citation: Record-breaking gene edit disables 13,200 LINE-1 Transposons in a single cell (2019, March 27) retrieved 18 August 2019 from https://phys.org/news/2019-03-record-breaking-gene-disables-line-transposons.html The CRISPR gene editing technique has made headlines around the world over the past several years as researchers have used it to edit genes in a variety of ways. More recently, researchers have attempted to make multiple edits to the same cell. Up until now, the record was 62 edits as part of an effort to remove remnants of retrovirus genes in a pig genome.The researchers explain that the reason they are working to perfect the multiple edit technique is to give them a way to remove LINE-1 transposons, also known as “jumping genes.” LINE-1 transposons are snippets of DNA that can move from one part of a genome to another, hence the nickname. Prior work has suggested that they are not necessary, and in fact, can lead to problems such as genetic diseases. Prior work has also shown that they make up approximately 17 percent of the human genome. That means that each cell has a lot of them, but getting rid of them one at a time would be a difficult challenge, to say the least. Because of that, the researchers with this new effort sought to get rid of them all in one fell swoop.The team notes that they first tried the regular CRISPR editing technique, but found that it resulted in a lot of collateral damage typically ending in cell death. The group then switched to using a version of CRISPR that has been modified into what has been described as a base editor—a gene editor that does not cut the DNA strand, but instead makes in-place letter swaps. Because it did not cut anything, the approach allowed the team to edit thousands of genes without killing the cell. The researchers note that the 13,200 edits they made represented just half of the LINE-1 transposons in the cell they were working on, but plan to continue working until they find a way to remove them all. More information: Cory J. Smith et al. Enabling large-scale genome editing by reducing DNA nicking, bioRxiv (2019). DOI: 10.1101/574020 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
The show will feature over a 250 exhibitors, including artists, writers and creator s from across India and abroad. Spread over 100,000 sq feet, it will feature the best and the brightest from the Pop-Culture universe in India and the world including experiential zones, the coolest merchandise and comics along with an awesome line up of Indian and International guests. Kristian Nairn, actor, HBO’s hit series Game of Thrones will be attending, taking special sessions, signing posters and speaking to fans at DCC. This is for the first time that Comic Con India is bringing in an International actor as a special guest to Delhi. Kristian is a Northern Irish actor and DJ. He is best known for his portrayal of Hodor in the HBO fantasy series Game of Thrones, where he initially appeared as a guest star in the first season and returned in this role for the second, third and fourth seasons. Also Read – ‘Playing Jojo was emotionally exhausting’When asked about the event Kristian Nairn said, “I am really excited and looking forward to attend Indian Comic Con in Delhi. I can’t wait to meet all the fans of Game of Thrones, will see you all soon in December!”Famous international personalities and Comic Book guests like Rob Denbleyker, author of Cyanide and Happiness, Ty Templeton, Canadian comic book artist and writer and Dinesh Shamdasani, CEO, Valiant Entertainment will be attending and taking special sessions at DCC 2015. Also Read – Leslie doing new comedy special with NetflixFor the sheer love for Comics, around 12 new titles will get launched at the convention. There will be International Exhibitors like Marvel Comics by Hachette India, DC, Dark Horse & Vertigo Comics by Random House India. Also, there will be some Awesome Anime & Manga Merch from Japanese Merchandiser IINE Toys, along with the best and most exclusive International merchandise at the convention from across the globe. Comic Con India is dedicated to creating unique events and giving the fans, exhibitors and partners a platform to celebrate their undying love and passion for comics and pop culture. Comic Con India is dedicated to expanding India’s popular culture by creating high profile events that cater to fans of not only comics, but also, gaming, movies, television, merchandise, toys and more.
Last week, GitHub announced that they have built a new integration to enable software teams to connect their code on GitHub.com to their projects on Jira Software Cloud. This integration updates Jira with data from GitHub, providing a better visibility into the current status of your project. What are the advantages of this new GitHub and Jira integration? No need to constantly switch between GitHub and Jira With your GitHub account linked to Jira, your team can see the branches, commit messages, and pull request in the context of the Jira tickets they’re working on. This integration provides a deeper connection by allowing you to view references to Jira in GitHub issues and pull requests. Source: GitHub Improved capabilities This new GitHub-managed app provides improved security, along with the following capabilities: Smart commits: You can use smart commits to update the status, leave a comment, or log time without having to leave your command line or GitHub View from within a Jira ticket: You can view associated pull requests, commits, and branches from within a Jira ticket Searching Jira issues: You can search for Jira issues based on related GitHub information, such as open pull requests. Check the status of development work: The status of development work can be seen from within Jira projects Keep Jira issues up to date: You can automatically keep your Jira issues up to date while working in GitHub Install the Jira Software and GitHub app to connect your GitHub repositories to your Jira instance. The previous version of the Jira integration will be deprecated in favor of this new GitHub-maintained integration. Once the migration is complete, the legacy integration (DVCS connector) is disabled automatically. Read the full announcement at the GitHub blog. Read Next 4 myths about Git and GitHub you should know about GitHub addresses technical debt, now runs on Rails 5.2.1 GitLab raises $100 million, Alphabet backs it to surpass Microsoft’s GitHub