Silva says Everton is unlikely to sign new players

first_imgThe Everton manager says the board has informed him that finances are not available to acquired new footballers in the January market transfer window.According to Everton boss Marco Silva, the team will not buy new players during the January market transfer window.Silva says the club’s board has informed him that finances are not available to acquire new footballers.“When you asked me the last few weeks the possible players coming or not in the market, I told you that you just can’t sign someone if someone leaves the club or we sell someone,” he told Sky Sports.Premier LeaguePremier League Betting: Match-day 5 Stuart Heath – September 14, 2019 Going into the Premier League’s match-day five with a gap already beginning to form at the top of the league. We will take a…“We don’t have the financial conditions to go in the market, [that] is the feedback I have at the moment. I have to find different solutions.”“It is not the moment for us to talk about player A, B, C or D [and] if they could interest our model as a team,” he added.“We have to work with the players we have here, develop them, let them get better every day. This is our job.”“What can happen in the market you know already, what are our possibilities as a club and my possibilities as a manager to do or not,” he commented.last_img read more

STUDENT SPOTLIGHT Wilmingtons Brent Sisters Graduate From Springfield College

first_imgSPRINGFIELD, MA — Springfield College congratulates its two graduates from Wilmington:Carli Brent has earned a bachelor’s of science degree in Communication Science and Disorders from Springfield College for studies completed in 2018.Christa Brent has earned a bachelor’s of art degree in English from Springfield College for studies completed in 2018.About Springfield CollegeFounded in 1885, Springfield College is known worldwide for the guiding principles of its Humanics philosophy-educating students in spirit, mind and body for leadership in service to others. With its foundation of academic excellence and rich athletic heritage, Springfield College prepares students with real-world leadership skills for careers that transform lives and communities. The college offers a range of undergraduate and graduate degree programs in the fields of health sciences, human and social services, sport management and movement studies, education, business, and the arts and sciences. It also offers doctoral programs in physical education, physical therapy, and counseling psychology. The college is ranked in the 2018 edition of “Best Colleges” in the top tier of “Best Regional Universities – North Region” by U.S.News & World Report, and is ranked one of the top schools in the North Region of the U.S.News Best Values report. It is also designated as a College of Distinction and a premier Leadership Development Center by the YMCA of the USA. Nearly 5,000 traditional, nontraditional and international students study at its main campus in Springfield, Mass., and at its regional campuses across the country.(NOTE: The above announcement is from Springfield College via Merit.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedSTUDENT SPOTLIGHT: Wilmington’s Lindsay Donahue Graduates From Springfield CollegeIn “Education”Bolis, Brent & Ferreira Named To Dean’s List At Springfield CollegeIn “Education”STUDENT SPOTLIGHT: 5 Wilmington Students Named To Dean’s List At Springfield CollegeIn “Education”last_img read more

5 Things To Do In Wilmington On Friday March 22 2019

first_imgWILMINGTON, MA — Below are 5 things to do in Wilmington on Friday, March 22, 2019:#1) Abundant Life’s Pasta Dinner & Silent AuctionAbundant Life Christian School’s 20th Annual Pasta Dinner and Silent Auction will be held at 5pm. Please consider joining us as we raise money to support the eighth grade trip to Washington, D.C.. Each year, the eighth grade has the opportunity to go on a class trip to see our nation’s capital and learn about the great history of this country while making memories to last a lifetime.The Pasta Dinner was first held back in April of 1999 and the Silent Auction was added in 2007. It has since become the most highly anticipated event of the year! It is a wonderful community event with food, fun and friends. The Pasta Dinner has two seatings, at 5pm and 6:30pm. Prices are $7 per ticket, with children 8 and under at $5. In addition, take-out orders are available.Come, relax, and be served by the eighth grade Class of 2019 and place your bids. For further information please contact Abundant Life Christian School at (978) 657-8710 or email tixalcs@gmail.com.#2) Wilmington Middle School Drama Club’s “Seussical The Musical”The Wilmington Middle School Drama Club presents its spring musical, “Seussicial The Musical” on Thursday, March 21, 2019 (7pm); Friday, March 22, 2019 (7pm); and Saturday, March 23, 2019 (1pm) in the Wilmington Middle School Auditorium. Come enjoy the story of Horton and some of our favorite Dr. Seuss characters. Tickets are available at the door. Tickets cost $10 for adults and $7 for students (12 and under).#3) Shawsheen/West PAC Trivia NightThe Shawsheen/West PAC is proud to announce its 6th Annual Trivia Night from 7pm to 11pm at the Tewksbury/Wilmington Elks (777 South Street, Tewksbury). Games begin at 7:30pm. Tickets cost $20 per person. Learn more HERE.#4) Wilmington Good Guy Nomination DeadlineNominations must be received by 5:00PM on Friday March 22, 2019. They can be mailed to the Wilmington Good Guy Committee, 9 Reed St. Wilmington MA 01887 or sent by email to: wgoodguy@verizon.net. Learn more HERE.#5) Karaoke At Pacific GrovePacific Grove (211 Lowell Street) is hosting karaoke from Winnell Entertainment beginning at 8pm.Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email wilmingtonapple@gmail.com.Share this:TwitterFacebookLike this:Like Loading… RelatedAbundant Life’s Pasta Dinner & Silent Auction Set For March 22In “Community”Abundant Life’s Silent Auction & Pasta Dinner Set For April 13In “Education”Abundant Life’s Silent Auction & Pasta Dinner Set For April 7In “Community”last_img read more

Shalom Ministries Hosts Family and Friends Day

first_imgShalom Ministries Christian Center will hold a family and friends day Sept. 21 for its 11 a.m. service. The service will include a guest psalmist, liturgical dancing and refreshments. The church is located at 515 Kerby Hill Road in Fort Washington. For more information, contact: Angie Edwards, 301-325-8890.last_img

Recordbreaking gene edit disables 13200 LINE1 Transposons in a single cell

first_img © 2019 Science X Network Explore further An international team of researchers has succeeded in making 13,200 edits to a single cell—and the cell survived. In their paper uploaded to the bioRxiv preprint server, the team describes the edits they made, how they did it and why. Credit: CC0 Public Domain Distorted, stretched DNA may increase risk of off-target changes with CRISPR-Cas9 Citation: Record-breaking gene edit disables 13,200 LINE-1 Transposons in a single cell (2019, March 27) retrieved 18 August 2019 from https://phys.org/news/2019-03-record-breaking-gene-disables-line-transposons.html The CRISPR gene editing technique has made headlines around the world over the past several years as researchers have used it to edit genes in a variety of ways. More recently, researchers have attempted to make multiple edits to the same cell. Up until now, the record was 62 edits as part of an effort to remove remnants of retrovirus genes in a pig genome.The researchers explain that the reason they are working to perfect the multiple edit technique is to give them a way to remove LINE-1 transposons, also known as “jumping genes.” LINE-1 transposons are snippets of DNA that can move from one part of a genome to another, hence the nickname. Prior work has suggested that they are not necessary, and in fact, can lead to problems such as genetic diseases. Prior work has also shown that they make up approximately 17 percent of the human genome. That means that each cell has a lot of them, but getting rid of them one at a time would be a difficult challenge, to say the least. Because of that, the researchers with this new effort sought to get rid of them all in one fell swoop.The team notes that they first tried the regular CRISPR editing technique, but found that it resulted in a lot of collateral damage typically ending in cell death. The group then switched to using a version of CRISPR that has been modified into what has been described as a base editor—a gene editor that does not cut the DNA strand, but instead makes in-place letter swaps. Because it did not cut anything, the approach allowed the team to edit thousands of genes without killing the cell. The researchers note that the 13,200 edits they made represented just half of the LINE-1 transposons in the cell they were working on, but plan to continue working until they find a way to remove them all. More information: Cory J. Smith et al. Enabling large-scale genome editing by reducing DNA nicking, bioRxiv (2019). DOI: 10.1101/574020 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

China sentences 8 to death for attacks in Xinjiang

first_imgThe Urumqi Intermediate People’s Court in the capital of Xinjiang also handed out suspended death sentences to five others, China Central Television said, without mentioning when the trials were held. In a separate case, the same court jailed seven minority students of a prominent Uighur scholar for three to eight years after convicting them of separatism, rights lawyer Li Fangping said Monday. Violence linked to Xinjiang has killed about 400 people in and outside the region over the past 20 months. Beijing has blamed the attacks on radical separatists with foreign ties, although critics and human rights advocates say Uighurs have chafed under the repressive rule of the Han Chinese-dominated government. Also Read – Pro-Govt supporters rally as Hong Kong’s divisions deepenUighurs also complain of economic disenfranchisement with the inflow of Han Chinese to their homeland. Beijing says it is pumping investments into the region to help it grow. Most attacks have been mounted against state targets, such as police stations, military checkpoints and government buildings, but assailants also have struck at civilians in several recent incidents, slashing at crowds with knives or setting off bombs at train stations and commercial areas.last_img read more

After RHEL 8 release users awaiting the release of CentOS 8

first_imgThe release of Red Hat Enterprise Linux 8 (RHEL 8) this week, has made everyone waiting for CentOS 8 rebuild to occur. The release of CentOS 8 will require major overhaul in the installer, packages, packaging, and build systems so that it can work with the newer OS. CentOS 7 was released last year, days after RHEL 7 was released. So far the team at CentOS have made their new build system setup ready, and are currently working on the artwork. But they still need to work on their multiple series of build loops in order to get all of the CentOS 8.0 packages built in a compatible fashion. There will be a an installer update followed by a release candidate(s). Only after all these releases, CentOS 8 will finally be available for it’s users. The RHEL 8 release has made many users excited for the CentOS 8 build. A user on Reddit commented, “Thank you to the project maintainers; while RedHat does release the source code anyone who’s actually compiled from source knows that it’s never push-button easy” Another user added, “Thank you Red Hat! You guys are amazing. The entire world has benefited from your work. I’ve been a happy Fedora user for many years, and I deeply appreciate how you’ve made my life better. Thank you for building an amazing set of distros, and thank you for pushing forward many of the huge projects that improve our lives such as Gnome and many more. Thank you for your commitment to open source and for living your values. You are heroes to me” So far, a release date has not been declared for CentOS 8 , but a rough timeline has been shared. To read about the steps needed to make a CentOS rebuild, head over to the CentOS wiki page. Read Next Red Hat releases OpenShift 4 with adaptability, Enterprise Kubernetes and more! Soon, RHEL (Red Hat Enterprise Linux) won’t support KDE Red Hat released RHEL 7.6last_img read more